Shimano E-Tube Project is limited to Windows and mobile devices (IOS/Android). If you don’t have access to a Windows PC (or have the Bluetooth module installed) it is possible to run the E-Tube Project for Windows within a virtual machine on a Mac and connect the SM-PCE1 PC Linkage or the SM-BCR2 battery charger via USB to manage your Di2 groupset.

Links:
Shimano E-Tube Project Website: https://bit.ly/3hIny9m
Virtual Box: https://bit.ly/31FEt6G
Windows 10 ISO: https://bit.ly/3lu8Bdf
Installing .NET Framework: https://bit.ly/3gHCD9J

Shimano Di2 Parts Used:
Shimano BT-DN110 Di2 Battery: https://amzn.to/2QbRWwO
Shimano Dura-Ace Di2 ST-R9150 11-Speed Shifters: https://amzn.to/31D8QuG
Shimano TL-EW02 Di2 E-Tube Plug Tool: https://amzn.to/3aIQvz3
Shimano PC Linkage SM-PCE1: https://bit.ly/3hK1ET3